New aerodynamic lens injector for single particle diffractive imaging

Nils Roth, Daniel A. Horke, Jannik Lübke, Amit K. Samanta, Armando D. Estillore, Lena Worbs, Nicolai Pohlman, Kartik Ayyer, Andrew Morgan, Holger Fleckenstein, Martin Domaracky, Benjamin Erk, Christopher Passow, Jonathan Correa, Oleksandr Yefanov, Anton Barty, Saša Bajt, Richard A. Kirian, Henry N. Chapman, Jochen Küpper: New aerodynamic lens injector for single particle diffractive imaging. In: Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, vol. 1058, pp. 168820, 2024, ISSN: 0168-9002.

Abstract

An aerodynamic lens injector was developed specifically for the needs of single-particle diffractive imaging experiments at free-electron lasers. Its design allows for quick changes of injector geometries and focusing properties in order to optimize injection for specific individual samples. Here, we present results of its first use at the FLASH free-electron-laser facility. Recorded diffraction patterns of polystyrene spheres are modeled using Mie scattering, which allowed for the characterization of the particle beam under diffractive-imaging conditions and yielded good agreement with particle-trajectory simulations. The complex refractive index of polystyrene at λ=4.5nm was determined as m=0.976−0.001i.

BibTeX (Download)

@article{ROTH2024168820,
title = {New aerodynamic lens injector for single particle diffractive imaging},
author = {Nils Roth and Daniel A. Horke and Jannik L\"{u}bke and Amit K. Samanta and Armando D. Estillore and Lena Worbs and Nicolai Pohlman and Kartik Ayyer and Andrew Morgan and Holger Fleckenstein and Martin Domaracky and Benjamin Erk and Christopher Passow and Jonathan Correa and Oleksandr Yefanov and Anton Barty and Sa\v{s}a Bajt and Richard A. Kirian and Henry N. Chapman and Jochen K\"{u}pper},
url = {https://www.sciencedirect.com/science/article/pii/S0168900223008112},
doi = {https://doi.org/10.1016/j.nima.2023.168820},
issn = {0168-9002},
year  = {2024},
date = {2024-01-01},
urldate = {2024-01-01},
journal = {Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment},
volume = {1058},
pages = {168820},
abstract = {An aerodynamic lens injector was developed specifically for the needs of single-particle diffractive imaging experiments at free-electron lasers. Its design allows for quick changes of injector geometries and focusing properties in order to optimize injection for specific individual samples. Here, we present results of its first use at the FLASH free-electron-laser facility. Recorded diffraction patterns of polystyrene spheres are modeled using Mie scattering, which allowed for the characterization of the particle beam under diffractive-imaging conditions and yielded good agreement with particle-trajectory simulations. The complex refractive index of polystyrene at λ=4.5nm was determined as m=0.976−0.001i.},
keywords = {crystallography, diffractive imaging, experimental design, nanoparticles, Simulation, Single-particle imaging, XFEL},
pubstate = {published},
tppubtype = {article}
}